The issues include erroneous email notifications, issues with apps, camera locking and with the HTC Sense UI. So it looks like HTC and Verizon have not tested the software update properly before releasing it to the public.
HTC has announced via Twitter that they are working with Verizon to have a solution ready very soon, and an update will be released to solve the issues that users are facing with their devices. Users will be notified once this update is ready.
Hopefully they will have the update properly tested before releasing it this time. It is important that hardware and software is properly tested before release as customers paying premium prices for products that don't perform optimally is just unacceptable.